PhD Studentship in Translational Immunopathology Research Group led by Dr Mary Canavan
Post Description: The Translational Immunopathology group led by Dr Mary Canavan (https://www.tcd.ie/Biochemistry/people/CANAVAM1/) is housed in the School of Biochemistry and Immunology and the School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin. The group uses state of the art ex vivo and in vitro methods on human biological samples to understand early immune dysregulation that drives the development, progression, and response to treatment in individuals with autoimmune diseases such as Inflammatory Bowel Disease and Rheumatoid Arthritis. The successful PhD candidate will work on an SFI funded project aimed at investigating the contribution of tissue resident memory T cells to Rheumatoid Arthritis (RA) disease onset, flare, and progression.
Standard Duties and Responsibilities of the Post: The PhD student will examine TRM frequency, function, and metabolism in RA patient biospecimens (blood and synovial tissue/synovial fluid). The successful candidate will gain experience in multi-colour spectral flow cytometry, immunofluorescence, primary cell culture and bioinformatics. Furthermore, due to the strong translational aspect of this project, the student will have the opportunity to work across a multidisciplinary team of consultants, clinical researchers, scientists, and patient partners across 3 sites, TBSI, St James Hospital and St Vincent’s University Hospital.
To apply:
successful applicant will be expected to have a first-class honours degree or a high upper second in any biological subject preferably with a significant immunology component. Please submit a covering letter and CV (include the names and contact details of 2 referees) with the Subject: PhD Application to: canavam1@tcd.ie
Deadline: 31 May 2024
More details on the role can be found in the document below:
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