14th and 15th September 2017

Tercentenary Hall,

Trinity Biomedical Sciences Institute, Trinity College, Dublin 2


Thursday, 14th September 2017
08:00 – 08:50 Conference Registration
08:50 – 09:00 Conference Open/Welcome: Prof. Ed Lavelle, Trinity College Dublin
President, Irish Society for Immunology
Chair: Dr. Beth Brint, University College Cork
09:00 – 09:40 Molecular mechanisms underlying the cellular decision to respond to inflammatory stimuli
Dr. Ruaidhri Carmody
University of Glasgow, U.K.
09:40 – 10:20 Disruption of macrophage/microglial metabolism in a model of Alzheimer’s disease
Prof. Marina Lynch
Trinity College Dublin, Ireland
10:20 – 11:00 Tea/Coffee, Posters and Trade Exhibitions
11:00 – 11:15 S01: A SNP in time: The effect of MALD96N in TLR signallingJennifer Dowling
Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, Victoria, Australia
11:15 – 11:30 S02: Molluscum Contagiosum Virus protein MC005 inhibits innate virus sensing and pro-inflammatory cytokine-mediated activation of the IKK complex and NFκB by targeting IKKγ/NEMO
Gareth Brady
Trinity College Dublin, Ireland
11:30 – 11:45 S03: Modulation of membrane fluidity regulates IL-10 production by dendritic cells
Sean McCluskey
Trinity College Dublin, Ireland
11:45 – 12:00 S04: IL-36 cytokines alter the composition of the intestinal microbiome to protect against obesity and metabolic dysfunction
Eirini Giannoudaki
National Children’s Research Centre, Our Lady’s Children’s Hospital and Trinity College Dublin, Ireland
12:00 – 12:50 Selected 3 min Flash Presentations Session I
Chair: Dr. Derek Doherty
Trinity College Dublin
12:50 – 13:45 Lunch, Posters and Trade Exhibitions
Chair: Prof. Padraic Fallon, Trinity College Dublin
13:45 – 14:25 Regulation of epithelial barrier in allergic diseases
Prof. Cezmi Akdis
Swiss Institute of Allergy and Asthma Research, Davos, Switzerland
14:25 – 15:05 Molecular re-classification of immune mediated diseases – a focus on systemic sclerosis
Prof. Dr. Timothy Radstake
UMC Utrecht, The Netherlands
15:05 – 15:20 S05: Tumour Infiltrating monocytes correlate with CD8+ T cells in a subset of colorectal cancer (CRC) tumours with high CCL3 and CCL5 expression and intact aerobic respiration.
Louise Elliott
St.Vincent’s University Hospital, Dublin, Ireland
15:20 – 15:35 S06: Investigating the role of IL-6 on macrophage phenotypes in fibrotic disease
Emma Doran
Genentech Inc., South San Francisco, California, USA.
15:35 – 15:50 S07: Distinct pathogenic mechanisms and transcriptomic signatures of joint specific CD141+ dendritic cells
Mary Canavan
Trinity College Dublin, Ireland
15:50 – 16:15 Tea/Coffee, Posters and Trade Exhibitions
16:15 – 16:55 Skin: immunity, reaction and vaccination
Dr. Bénazine Combadiere
INSERM, Paris, France
17:00 – 19:00 Posters, Wine Reception and Trade Exhibitions
19:00 – 23:00
Banquet Dinner – Ely Brasserie
Friday, 15th September 2017
Chair: Dr. Denise Fitzgerald, Queen’s University, Belfast
09:00 – 09:40 Circadian rhythms in adaptive and innate immunity
Dr. Christoph Scheiermann
Ludwig-Maximilians Universitat University, Munich, Germany
09:40 – 10:20 T cells and TB –friends or foes?
Prof. Andrea Cooper
University of Leicester, U.K.
10:20 – 10:45 Tea/Coffee, Posters and Trade Exhibitions
10:45 – 11:25 Death receptors, inflammation and cancer
Prof. Seamus Martin
Trinity College Dublin, Ireland
11:25 – 11:40 S08: Prostaglandin E2 protects against caspase-11 – induced cell death.
Zbigniew Zaslona
Trinity College Dublin, Ireland
11:40 – 11:55 S09: Obesity induces metabolic reprogramming in natural killer cells leading to defects in cancer immune surveillance
Lydia Dyck
Trinity College Dublin, Ireland and Harvard Medical School
11:55 – 12:10 S10: TLR2 bridges oxidative stress and complement activation in a model of Age-related macular degeneration (AMD)
Kelly Mulfaul
The National Children’s Research Centre, Our Lady’s Children’s Hospital, Dublin, Ireland
12:10 – 13:00 Selected 3 min Flash Presentations Session II
Chair: Dr. Annie Curtis
Royal College of Surgeons in Ireland
13:00 – 14:00 Lunch, Posters and Trade Exhibitions
Chair: Prof. Paul Moynagh, Maynooth University
14:00 – 14:40 Islet inflammation in type 2 diabetes: from physiology to therapy
Prof. Mark Donath
University of Basel, Switzerland
14:40 – 14:55 S11: Interleukin-17 receptor A regulates cutaneous immunity to maintain the integrity of the skin barrier to prevent allergic skin inflammation
Achilleas Floudas
Trinity College Dublin, Ireland
14:55 – 15:10 S12: Arginase-2 is essential for mitochondria-associated functions in M2-polarised macrophages.
Claire McCoy
Hudson Institute of Medical Research, Monash University, Australia and Royal College of Surgeons in Ireland
15:10– 15:25 S13: NOD1 and NOD2 activation prevent autoimmune disease through innate immune training
Mark Lynch
Trinity College Dublin, Ireland
15:25 – 15:50 Tea/Coffee, Posters and Trade Exhibitions
15:50 – 16:30 Warburg meet macrophages: how metabolic reprogramming is providing new insights into immunoregulation and inflammation
Prof. Luke O’Neill
Trinity College Dublin, Ireland
16:30 – 17:00 Award of Presentation Prizes
Close of Conference