19th & 20th September 2019
 O’Flanagan Lecture Theatre
Royal College of Surgeons in Ireland (RCSI)


ISI 2019 Meeting – Programme


Please click here to download a copy of the ISI Meeting 2019 Poster to display in your institute.


Thursday, 19th September 2019
08:00 – 09:05 Conference Registration
09:05 – 09:15 Conference Open/Welcome:

Prof. Ed Lavelle, Trinity College Dublin President, Irish Society for Immunology

Chair and Co-Chair: Claire McCoy (RCSI) and Richie Carroll (RCSI)
09:15 – 09:55 Environment control of T cell function

Doreen Cantrell
University of Dundee, Scotland

09:55 – 10:10 S01: Training of hematopoietic stem cells by helminth products induces long-term trained immunity that protects against autoimmune disease.

Kyle Cunningham, Trinity College Dublin

10:10 – 10:25 S02: Nutritional restrictions of Dendritic cells promote effector T cell functions via cytokine signalling

Diana Moreira, Trinity College Dublin

10:25 – 10:55 Tea/Coffee, Posters and Trade Exhibitions
10:55 – 11:35 Dendritic cells beyond immunity

David Sancho
CNIC, Madrid, Spain

11:35 – 11:50 S03: The core clock protein BMAL1 regulates antigen processing in dendritic cells by altering cellular calcium location to control mitochondrial morphology
Mariana Cervantes, Royal College of Surgeons in Ireland
11:50 – 12:05 S04: Immune checkpoint blockade reverses obesity-associated defects in anti-tumour immunity
Lydia Dyck
, Trinity College Dublin
12:05 – 13:00 Selected 3 min Flash Presentations Session I – PhD Students
Chair: Kingston Mills, Trinity College Dublin
13:00 – 14:00 Lunch, Posters and Trade Exhibitions
Chair and Co-Chair: Pat Walsh (TCD) and  Shauna Quinn (TCD)
14:00 – 14:40 Tolerance tuning via GPCR-sensing of bacterial-derived metabolites

Liam O’Mahony
APC, University College Cork, Ireland

14:40 – 14:55 S05:  Complexity of pleural cavity macrophages during filarial nematode infection.
Conor Finlay, University of Manchester, UK
14:55 – 15:10 S06: The Mal-Interferon-gamma receptor axis is a key modulator of inflammation and susceptibility during pneumococcal disease
Natalia Munoz-Wolf
, Trinity College Dublin
15:10 – 15:40 Tea/Coffee, Posters and Trade Exhibitions
15:40 – 15:55 S07: Friend retrovirus infection induces the development of memory‑like natural killer cells
Elisabeth Littwitz-Salomon, University of Essen, Germany and Trinity College Dublin,
15:55 – 16:10 S08: Stimulation of Human Vδ2+ T cells by the HMBPP-negative Gram-positive Bacterium Staphylococcus aureus
Andrew Cooper, Trinity College Dublin
16:10 – 16:50 Helminth infections, immune modulation and insulin resistance

Maria Yazdanbakhsh
LUMC, Leiden University Medical Centre, The Netherlands

17:00 – 19:00 Posters, Wine Reception and Trade Exhibitions -RCSI, Exam Hall
19:00 – 23:00
Banquet Dinner – RCSI, College Hall
Friday, 20th September 2019
Chair and Co-Chair: Niall Conlon (St. James Hospital) and Melissa Conroy (TCD)
09:00 – 09:40 How early can we predict development of RA?

Ursula Fearon 
Trinity College Dublin

09:40 – 10:20 Joint perspectives: investigating synovial inflammation in rheumatoid and psoriatic arthritis

Leonie Taams
Kings College London

10:20 – 10:35 S09: CNA activation can improve immune responses to ALUM and other potential vaccine adjuvants in neonates
Kiva Brennan, National Children’s Research Centre, Crumlin and Trinity College Dublin
10:35 – 10:50 Engineering adoptive T cell therapy to co-opt Fas ligand-mediated death signaling in solid tumors
Kristen G. Anderson
, Fred Hutchinson Cancer Research Center, Seattle, USA
10:50 – 11:20 Tea/Coffee, Posters and Trade Exhibitions
11:20 – 11:35 S10: Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis
Joanne Masterson, Maynooth University
11:35 – 12:15 Integrative cancer immunology and immune contexture

Jerome Galon
CRC, Paris

12:15 – 13:15 Selected 5 min Flash Presentations Session II Post Doctoral Researchers
Chair: Aideen Ryan, National University of Ireland, Galway (NUIG)
13:15 – 14:20 Lunch, Posters and Trade Exhibitions
Chair and Co-Chair: Paul Moynagh (Maynooth University) and Jen Dowling (RCSI)
14:20 – 15:00 TLR signaling rewires macrophage metabolism to license inflammatory responses

Eicke Latz
University of Bonn, Germany

15:00 – 15:15 S11: Negative regulation of caspase-11 by Prostaglandin E2: a role for caspase-11 in asthma
Zbigniew Zaslona, Trinity College Dublin
15:15 – 15:30 S12: SARM regulates IL-1 production yet contributes to pyroptosis following AIM2 inflammasome activation
Michael Carty
, Trinity College Dublin
15:30– 16:00 Tea/Coffee, Posters and Trade Exhibitions
16:00 – 16:40 How genetic risk variants of age-related macular degeneration promote the pathogenic accumulation of mononuclear phagocytes

Florian Sennlaub
Vision Institute, Paris, France

16:40 – 17:20 Engineering new therapies at the interface of coagulation and immunity

Roger Preston
Royal College of Surgeons in Ireland, Dublin

17:20 – 17:30 Award of Presentation Prizes
Close of Conference

Please click here to download a copy of the SI Meeting 2019 Poster to display in your institute.